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CME / ABIM MOC

Management of HR-Positive/HER2-Negative Early Breast Cancer: Taking Direction From the Updated Guidelines

  • Authors: Joyce O'Shaughnessy, MD; Nadia Harbeck, MD, PhD; Kevin Kalinsky, MD, MS
  • CME / ABIM MOC Released: 3/27/2023
  • THIS ACTIVITY HAS EXPIRED FOR CREDIT
  • Valid for credit through: 3/27/2024, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for oncologists, surgeons, and obstetrician/gynecologists.

The goal of this activity is for learners to be better able to manage hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative early breast cancer (EBC) and discuss the rationale behind these recommendations based on the latest clinical guidelines.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Guideline recommendations regarding the management of patients with HR-positive/HER2-negative EBC
  • Have greater competence related to
    • Implementing the latest guidelines in clinical practice
  • Demonstrate greater confidence in their ability to
    • Optimize treatment decisions for patients with HR-positive/HER2-negative early breast cancer in accordance with the latest guidelines


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


Faculty

  • Joyce O'Shaughnessy, MD

    Celebrating Women Chair in Breast Cancer Research
    Baylor University Medical Center
    Director
    Breast Cancer Research Program
    Texas Oncology
    US Oncology
    Dallas, Texas, United States

    Disclosures

    Joyce O'Shaughnessy, MD, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie, Inc.; Agendia; Amgen, Inc.; Aptitude Health; AstraZeneca; Athenex; Bayer; Bristol Myers Squibb Company; Carrick Therapeutics; Celgene Corporation; Daiichi Sankyo, Inc.; Eisai, Inc.; G1 Therapeutics; Genentech, Inc.; Genzyme Corporation; Gilead Sciences, Inc.; GRAIL; Halozyme Therapeutics; Heron Therapeutics; Immunomedics, Inc.; Ipsen; Lilly; Merck; Myriad; Nektar Therapeutics; Novartis; Ontada; Pfizer, Inc.; Pharmacyclics, Inc.; Pierre Fabre; Puma Biotechnology; Roche; Samsung Bioepis; Sandoz; Sanofi; Seagen Inc.; Syndax Pharmaceuticals, Inc.; Taiho Pharmaceutical Co., Ltd.; Takeda; Theralink Technologies; Synthon BV

  • Nadia Harbeck, MD, PhD

    Director of Breast Cancer
    Department of Obstetrics and Gynecology
    LMU University Hospital
    Munich, Germany

    Disclosures

    Nadia Harbeck, MD, PhD, has the following relevant financial relationships:
    Consultant or advisor for: Gilead Sciences, Inc.; Novartis; Roche; Sanofi; Sandoz; Seagen Inc.
    Speaker or member of speakers’ bureau for: AstraZeneca; Daiichi Sankyo, Inc.; Gilead Sciences, Inc.; Lilly; Merck Sharp & Dohme GmbH; Novartis; Pierre Fabre; Pfizer, Inc.; Roche; Sandoz; Sanofi; Seagen Inc.; Viatris 
    Research funding from: AstraZeneca; Bristol Myers Squibb Company; Daiichi Sankyo, Inc.; Merck Sharp & Dohme GmbH; Roche; Pfizer, Inc.

  • Kevin Kalinsky, MD, MS

    Associate Professor
    Department of Hematology and Medical Oncology
    Emory University School of Medicine
    Louisa and Rand Glenn Family Chair in Breast Cancer Research
    Director
    Glenn Family Breast Center
    Director
    Breast Medical Oncology
    Winship Cancer Institute of Emory University
    Atlanta, Georgia, United States

    Disclosures

    The opinions expressed are those of Dr Kalinsky and do not necessarily reflect the views of Emory University or Emory Healthcare. Dr Kalinsky's participation in this activity does not constitute or imply endorsement by Emory University or Emory Healthcare.

    Kevin Kalinsky, MD, MS, has the following relevant financial relationships:
    Consultant or advisor for: 4D Pharma; AstraZeneca; Cyclocel; Daiichi Sankyo, Inc.; Eisai, Inc.; Immunomedics, Inc.; Lilly; Merck; Novartis; Oncosec; Pfizer, Inc.; Puma Biotechnology; Seagen Inc.

Editor

  • Victoria Phoenix, BS

    Medical Education Director, Medscape, LLC

    Disclosures

    Victoria Phoenix, BC, has no relevant financial relationships.

Compliance Reviewer

  • Amanda Jett, PharmD, BCACP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Amanda Jett, PharmD, BCACP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements

Medscape

Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    The European Union of Medical Specialists (UEMS)-European Accreditation Council for Continuing Medical Education (EACCME) has an agreement of mutual recognition of continuing medical education (CME) credit with the American Medical Association (AMA). European physicians interested in converting AMA PRA Category 1 credit™ into European CME credit (ECMEC) should contact the UEMS (www.uems.eu).

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

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  1. Read about the target audience, learning objectives, and author disclosures.
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  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC

Management of HR-Positive/HER2-Negative Early Breast Cancer: Taking Direction From the Updated Guidelines

Authors: Joyce O'Shaughnessy, MD; Nadia Harbeck, MD, PhD; Kevin Kalinsky, MD, MSFaculty and Disclosures
THIS ACTIVITY HAS EXPIRED FOR CREDIT

CME / ABIM MOC Released: 3/27/2023

Valid for credit through: 3/27/2024, 11:59 PM EST

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Educational Impact Challenge

The goal of this activity is for learners to be better able to manage hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative early breast cancer (EBC) and discuss the rationale behind these recommendations based on the latest clinical guidelines.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

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